Wednesday , March 29 2023

A new approach to antibiotic-resistant bacteria


Are the antibiotic-resistant bacteria dangerous now?

The new method allows antibiotics to be more effective and kill antibiotics-resistant bacteria. Thus, researchers are now thinking about effective treatment of antibiotics-resistant bacteria.

Recent research by the University of North Carolina has revealed that the use of special molecules makes certain antibiotics 100 times more beneficial than Staphylococcus aureus. The results of the research were published in the journal "Cellular Chemical Biology" in English.

When bacterial strains are resistant to antibiotics, even simple diseases can cause death. (Photo: Zerbor /

How do antibiotics-resistant bacteria develop?

Antibiotics for the prevention and treatment of bacterial infections. In response to these drugs, they become resistant to antibiotics as bacteria change. This means that treatments are very difficult. Unfortunately, the growth of antibiotic-resistant bacterial strains continues. One of the most dangerous contributors today is methicillin-resistant Staphylococcus aureus (MRSA). This is a regular type of bacteria, which often affects health workers and leads to life-threatening infections.

How to treat antibiotics-resistant bacteria

There is a great need for new ways to kill standard bacteria resistant to standard antibiotics. According to researchers, the change in membrane permeability that affects the deposition of aminoglycosides is an effective method against Staphylococcus aureus. Succeeds in releasing external membranes of bacteria known as rammollipides, allowing amino acids to penetrate easily and quickly into molecules. The new method helps many people to cope with a super-pathogenic disease, which often causes severe complications because they can not be cured. This can save many lives in the world.

Why do many treatments do not work in staphylococcus strains?

For most staphylococcal strains, conventional treatment can not kill bacteria due to two factors: antibiotic resistance or low sensitivity. Bacterial metabolism can be adapted to life, even in people with oxygen-free areas, such as lungs of cystic fibrosis. In this case, bacteria are adapted to the environment and affect amino-glycoside antibiotics (including ribramycin) on an external wall or membrane. In a recent study by researchers, gnomolipids have found that intramuscinabol may increase the bacterial capacity.

Combination of antibiotics with ramnolipids has improved

In a number of experiments, researchers tested the combinations of ramolilid-epidemicin with staphylococcal disease, which were difficult to remove by conventional methods. They have improved the effect of ramnolipid tinctophysin on the staphylococcal disease, the serum group-resistant S. aureus strains and some strains resistant to antibiotics in patients with group fibrosis against MRSA. Tobramycin doses tend to have a smaller effect on the Staphylococcus aureus populations, or are often associated with gonadsolipids, the study said.

Rheniolipids successfully release the bacterial external membranes, allowing the antibiotic to penetrate easily and quickly. The team checked several antibiotics, including potassium, Tobramycin, Amicalcin, Gentamicin and Kanamycin. The effectiveness of antibiotics has increased not only in Staphylococcus aureus, but also on bacterial species Clostridium difficile.

Additional research is required

Further studies are needed to improve the effectiveness of existing therapy and reduce the resistance to antibiotic resistance, as bacterial interactions can have an effect on the efficacy of antibiotics. Here's a great way to increase the effectiveness of antibiotics – very promising. (As)


  • Lauren Radlinski, Sarah E. Row, Robert Brzozowski, Rennes Huguang, Praghetus Esvara and others: Chemical induction for aminoglycoside administration Staphylococcus aureus overcomes antibiotic resistance and endurance; Cellular Chemistry Biology (Help: 08/16/2019), Cellular Chemical Biology

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