A group of Chilean researchers have made significant progress in fighting the Alzheimer's disease by detecting the relationship between brain activation and the sugary metabolism in the brain.
Research by physicians Nibaldo Inestrosa and Pedro Cisternas, At the Center for Aging and Recovery at the Catholic University of California (CARE Chile UC), has developed a well-developed method of improving animal cognitive potential.
According to Cisternas, according to the EFE agency, animal research "tells about it Activating Wnt stimulates glucose metabolism, mainly in neurons, is a very important process in the brain, especially for horizontal and hippocampus, as well as many glucose and energy-intensive organs for proper functioning in the regions concerned with memory and learning processes.
His brain is about 2% of body weight, but requires 20% of human body and 25% of oxygen (a fundamental nucleotide in cellular energy production).
ATP, called Cysternas, is the amount of energy it receives for cellular functions, and in this regard, glucose metabolism decreases in almost all neurodegenerative diseases, such as Alzheimer's, Parkinson's and Ginanton's. this is due to the brain's ability to use glucose. "
In turn, Nibaldo Inestroza, a laureate of the National Science Award, explained that Alzheimer's worsened as a result of the accumulation of an insoluble protein called beta amyloid, which disturbs the neuron-binding signaling function. .
Therefore, by restoring the path of Wnt, you can restore contact between brain cells and prevent injury.
Based on this, Researchers develop different strategies for Wnt signalization activation, To promote the onset or development of Alzheimer's disease.
"We want to improve it treatment For the Molecules and Alzheimer 's patients, this project has the advantage that most of the project loses memory loss. It can affect the victims and their families, "said Dr. Chistnnas.
This discovery aims to improve the quality of life of Alzheimer's patients.