Saturday , June 3 2023

Mannose, "delicious" sugar, reduces tumor growth


An investigation into the United Kingdom, monosaccharidesas known mannose, in vegetables, oranges and apples tumors and increases the effect chemotherapy.

Tests have been made in mice with many mice and have to be tested in humans, but this is a step to understand how mannequins are used. helps malignant tumors, researchers said, referring to Cancer Reseach UK

Cancer uses more glucose than normal and healthy tissues. However, it is difficult to control glucose levels in your body with diet. In the present study, mannose It can interfere with glucose to reduce the sugar consumption of cancer cells.

Kevin Ryan, a leading author of the Beatconon Cancer Research Institute, says: "Glucose is a must have grown on tumors, so you should limit the amount of its use slows the development of malignant neoplasms. The problem is that normal tissues need glucose, so we can not get it from the body. «

"In our study, we found the manna dose, which suppresses glucose enough to slow the growth of tumors in the mice, but it does not seem to be exposed to normal tissue." This is a preliminary study, but this is a great way to find the perfect balance in the future introduction of mannose on cancer patients It improves chemotherapy without damaging your health. «

How did the researchers first determine whether the mice were suffering from a blood clot, lung or skin cancer? mannose drinking water and oral treatment. Addition of the mixture significantly reduced the growth of tumors and did not have a significant adverse effect.

Mice were treated with cisplatin and doxorubicin, one of the most commonly used chemotherapy to test how mannosis affects malignant tumors. They are dear mannose increase the effect of chemotherapy, reduce tumor growth, reduce the amount of tumors and increase the survival rate of some mice.

Other types of malignant neoplasms such as leukemia, osteosarcoma, ovarian and intestinal cancer were investigated. The researchers were treated with mannose to see if they were able to grow cancer cells in the laboratory and then grow.

Some cells responded well to treatment, and others did not. It has also been discovered that the enzyme has been damaged mannose cells This was a good indication of how effective treatment was.

Professor Kevin Ryan adds: "Our next step is to investigate why some of the treatment cells work to determine how patients benefit from these treatments. We hope to start manning clinical trials in humans as soon as possible to identify their new potential oncology therapy «

Mannose is sometimes used in a short time to treat urinary tract infections, but its long-term effect has not been studied. It is important to have a large number of studies because it can be used in patients with mannose cancer.

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