Thursday , August 11 2022

Tetra, Mexican fish that helps to repair the human heart



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A Mexican fish can hide the key to changing the lives of thousands of people suffering from heart disease.

Tetra, whose name is called Astyanax Mexicanus, which can repair heart tissue without scarring.

Thanks to the research funded by the British Heart Foundation, three areas of the genome gene relate to the ability to restore this tissue.

Dr. Mattold Mommersert and his researcher Oxford University team they studied two types of Mexican tetrae: they can cure those who live on the river and treat heart tissue and can not live in the cave.

Fish in the caves lived in the rivers north of Mexico, but 1.5 million years ago they were drifting into the cave with a flood and dwelling in the dark, so they were invisible and lost their color.

Compared with two types of tetra, researchers have found that two genes (lrrc10 and caveolin) in river fishes are much more active after heart failure.

Then scientists went out lrrc10 gene in other types of fish self-medication, zebbrish.

Without this gene, Zebbrish was unable to recover his heart.

It is known that both genes are involved and depend on heart condition called lrrc10 chronic cardiomyopathy.

The authors of the study say that it is possible to restore damaged hearts in one day by artificial transformation of how these and other genes work.

We had to do that use of medicines or genetic processing methods, where DNA has been modified, destroyed or replaced, such as Crispr-Cas9.

"I think fish can tell us how we really can really regenerate a person's heart," says Dr. Mommersstraff, Associate Professor of the Department of Medicine and Regeneration.

"It is early for us, but we are very glad that we have the potential to live with these impressive fish and people's broken hearts," he said.

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