I believe in the path of progress in science and medicine, and human health will improve for hundreds of years. While I was developing my career in medicine, I continued to optimistically.
Now I have great doubts.
Science is still working well, but the deadly barriers between my research and progress: Antibiotics.
It poses a threat to humanity and it is getting worse every day, but my colleagues and my colleagues are dissatisfied with the motives for doing so.
This week (November 12-18) is the World Antibiotic Knowledge Week. We need to talk about this danger. It is necessary to stimulate the opening and development of antibiotics, development of public-private partnership models for financing and investment.
It caused penicillin
The problem is that 75 years ago, science penetrated the use of penicillin, a new era in the control of infectious diseases, as was done in advance of sanitation. Infections such as pneumonia and streptocommunications have been fatal in the days of my father and mother, for at least a while.
After more than 25 years of life in later generations, infectious disease falls from No. 1 among all the causes of death, where it was higher in world wars than bullets and bombs.
In countries with low, rich and effective antibiotics, people have decided to follow the infection.
But all this time, when we live well, lives long and infectious diseases are working again, and today they are crashing at the door. In fact, they are breaking the door.
The market does not meet the demand
In a rapidly-set example of Darwin's adaptation through natural selection, bacteria and other microbes develop to survive antibiotics. They will continue to adapt and will succeed if humans do not form new protective layers in the form of new antibiotics and other creative approaches.
The governments of the world recognize the crisis because they are in the 2016 United Nations General Assembly Special Session and approved by the G20 in 2017.
Anxiety – we know what we need to do to make new antibiotic treatments, but work is very hard, there are new promising new alternatives to obsolete preparations, and more.
Unfortunately, they are not yet available in the commercial market, and they do not change anything if nothing changes in their way – not drugs, but as commodities.
The difficult obstacle to the production of new antibiotics is our economic model, which relies on market demand. An invisible philosopher and economist named Adam Smith, who does not work here and poses a threat, is all the possible accomplishments of antibiotics.
Canada can fight for life after antibiotics in the world
The public model is dangerous
In the US last summer, two pharmaceutical companies have approved the FDA for new antibiotic compounds. Their markets have fallen after markets have produced these drugs that can save the world.
The opposite is intuitive, is not it? It is dangerous to spend hundreds of millions of dollars to build, test, and market a new drug if the drug can not return the investment within 20 years before patent expires.
It's hard to do this while trying to recover this cost with a 10-day recipe. And while you are only setting up a new drug for infectious diseases that can not be resolved with traditional antibiotics, it still works in many ways.
The only way to increase the business sense of creating new antibiotics is to make them astronomical expensive, rare oncologic drugs, and who pays for it?
Many people say that we look at the fire departments and look at the antibiotics. As individuals, we may never need them, but we are ready to share their expenses as we wait for them to be.
The public model seems to have meaning, but who can get the political risk?
Hospitals are in danger
Without incidents – the end result of terribly effective antibiotics, if people are cooperating with the private sector to encourage, fund, and invest in antibiotic drugs all over the world through their governments.
It will be gradual, but it will definitely happen. The early stages are already present in the form of many infectious diseases that are endangering the basic functions of hospitals.
Further, general procedures, such as dental hygiene appointment and joint replacement, will be terminated due to the risk of infection.
People of all ages die from diseases that are used to treat $ 10 or $ 20 pills. The non-lethal people often get sick and take care of them for a long time.
Where can the life span begin at the beginning of the 1900s, and the golden epoch of antibiotics was a short, happy dance in history.
This can not be true. Allows us to turn our understanding into action.