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Micro-RNAs with DNA molecules are involved in autism



Micro-RNAs with DNA molecules are involved in autism

Source: Scienceetavenir.fr

12/11/2018 10:03

The Emory University and the Chinese Academy of Sciences have studied the role of micro-RNA in the development of autism spectrum disorders. And imagine an effective treatment of mice.

Genetic causes of autism are well-known. In one study, microorganisms, called MIR-137, develop in the disease. What is Micro-RNA? This is a small molecule close to DNA, but it is impossible to encode proteins that function in the cell. Micro-RNA (also known as miRNA) is used to regulate biological processes such as the development, differentiation, growth and metabolism of cells. By stopping the synthesis of proteins or by stopping the protein synthesis, the stimulus breaks the gene expression of various genes by discriminatory RNA.

In recent years, several studies have been published (in particular, Ebrahim Mahmoudi and Murray Cairns Nature Molecular Psychiatry 2017), MIR-137 plays an important role in brain functioning. In fact, it regulates several hundred genes. When this is unsuccessful, the activity of these genes deteriorates, leading to cellular disorders leading to neuropsychiatric disorders, including autism. However, the precise mechanics of this phenomenon are poorly understood. This is a lack of research by Emory University and researchers from the Chinese Academy of Sciences. Nature Neuroscience …

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